Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN)
About This Study

Lower urinary tract dysfunction (LUTD) is common in both men and women, and the incidence and prevalence increase with advancing age. The effects and burden of LUTD to individuals and the nation are enormous. Recent analysis showed that the prevalence of urinary incontinence (one of many symptoms of LUTD) was 51% in women and 14% in men aged 20 years and older. When the aging of the population is taken into account, the financial challenge caused by bothersome LUTD is expected to increase dramatically. Treatments for these symptom-based disorders are only modestly effective at best, have significant side-effects, wane in their effect over time, and are costly.

The Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) is a research consortium funded through the National Institutes of Health (NIH)/National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The LURN Network is comprised of six US clinical sites and a data coordinating center (DCC).

The long term goal of the LURN network is to develop and test measurement tools to describe symptoms of lower urinary tract dysfunction (LUTD) in women and men. The group plans to study targeted populations of patients with LUTD in order to expand our understanding of the causes of symptoms of LUTD and common ways that symptoms change over time. The researchers will also collect biosamples from patients for current and future study of LUTD. Through these activities, investigators hope that their efforts will inform strategies to prevent and/or manage disease and improve the lives of patients who suffer from the symptoms of LUTD.

Participating Institutions

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