The LURN Comprehensive Assessment of Self-Reported Urinary Symptoms (LURN CASUS) was developed as a comprehensive questionnaire for both men and women. The instrument was developed as a phenotyping tool to provide granular and precise information on lower urinary tract symptom experience, as well as a resource from which clinical tools and outcome measures could be developed. The items assess a wide range of symptoms including storage, voiding, post-micturition, urgency, incontinence, and abnormal bladder sensations.
Using items from the LURN CASUS, the LURN Symptom Index-29 (LURN SI-29) and the LURN Symptom Index-10 (LURN SI-10) were developed as patient-reported outcome (PRO) measures to assess urinary symptoms in adult men and women. The LURN SI-29 and LURN SI-10 are intended for use among individuals with urinary symptoms in general, including overactive bladder, pelvic floor disorders, stress urinary incontinence, urgency incontinence, mixed incontinence, nocturia, hesitancy, and post-void dribbling. The LURN SI-29 and LURN SI-10 assess urgency, incontinence, voiding difficulty, nocturia, pain, frequency and post-micturition symptoms over the past 7 days.
LURN is grateful to the PLUS Consortium for the Spanish translation of the SI-10, funded by the following NIDDK awards: U24DK106786, U01DK106853, U01DK106858, U01DK106898, U01DK106893, U01DK106827, U01DK106908, U01DK106892, U01DK126045.
Weinfurt KP, Griffith JW, Flynn KE, Cella D, Bavendam T, Wiseman JB, Andreev VP, Lai HH, Liu AB, Kirkali Z, Cameron AP, Bradley CS, and the LURN Study Group. The Comprehensive Assessment of Self-Reported Urinary Symptoms: A New Tool for Research on Subtypes of Patients with Lower Urinary Tract Symptoms. J Urol 2019 Jun; 201(6): 1177-1183. PMID: 30730410. PMCID: 6573020.
Cella D, Smith AR, Griffith JW, Flynn KE, Bradley CS, Gillespie BW, Kirkali Z, Talaty P, Jelovsek JE, Helfand BT, Weinfurt KP, and the LURN Study Group. A new outcome measure for LUTS: Symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index‐29 (LURN SI‐29) questionnaire. Neurol Urodyn. 2019; 38(6):1751-9. PMID: 31225927. PMCID: 6660359.
Cella D, Smith AR, Griffith JW, Kirkali Z, Flynn KE, Bradley CS, Jelovsek JE, Gillespie BW, Helfand BT, Talaty P, Weinfurt KP, and the LURN Study Group. A New Brief Clinical Assessment of Lower Urinary Symptoms for Women and Men: LURN SI-10. J Urol 2020 Jan; 203(1):164-170. PMID: 31364922. PMCID: 6904437.
Culpan M, Acar HC, Cella D, Tahra A, Cakici MC, Efiloğlu Ö, Atis G, Yildirim A. Turkish Validation and Reliability of the Symptoms of Lower Urinary Tract Dysfunction Research Network Symptom Index‐29 (LURN SI‐29) Questionnaire in Patients with Lower Urinary Tract Symptoms. Neurol Urodyn. 2021; 40(8):2034‐2040. PMID: 34499765.